Stephen Jones's Articles in Fitness

  • TLR10- cluster of differentiation 290
    Toll-like receptor 10 (TLR10) often known as CD290 (cluster of differentiation 290), is the most recently identified human homolog of the Drosophila TOLL protein. Human TLR10 is an orphan member of the Toll-like receptor family that recognizes pathogen-associated molecular pattern.
  • TLR9- cluster of differentiation 289
    Toll-like receptor 9 (TLR9) often known as CD289 (cluster of differentiation 289), is a member of the Toll-like receptor family that recognizes pathogen-associated molecular pattern. TLR9 was first cloned and identified as a receptor for unmethylated CpG-DNA as well as for bacterial DNA.
  • TLR8- cluster of differentiation 288
    Toll-like receptor 8 (TLR8) often designated as CD288 (cluster of differentiation 288) is a member of evolutionarily conserved Toll-like receptor family which are critical parts of the evolutionarily conserved innate immune system.
  • TLR7- cluster of differentiation 287
    Toll-like receptor 7 (TLR7), is an immune gene possessed by humans, other mammals and additionally in avian species playing a significant role in initiating antiviral immune responses.
  • TLR6- cluster of differentiation 286
    Toll-like receptor 6 (TLR6) often designated as CD286 (cluster of differentiation 286), is a member of the Toll-like receptor family, a highly conserved series of ancient innate immune pattern recognition receptors.
  • TLR5- cluster of differentiation 285
    Toll-like receptor 5 (TLR5), a member of the evolutionarily conserved Toll-like receptor family, has evolved to permit mammals specifically to detect flagellated bacterial pathogens.
  • TLR4- cluster of differentiation 284
    Toll-like receptor 4 (TLR4) often designated as CD284 (cluster of differentiation 284) is a class I transmembrane receptor belonging to the large homologous family of Toll like receptors.
  • TLR3- cluster of differentiation 283
    Toll-like receptor 3 (TLR3) often designated as CD283 (cluster of differentiation 283) is a type I transmembrane receptor protein. It belongs to a family of evolutionary conserved innate immune recognition molecules and recognizes double-stranded RNA, a molecular pattern associated with viral infections.
  • TLR2- cluster of differentiation 282
    Toll-like receptor 2 (TLR2), often designated as CD282 (cluster of differentiation 282) is a type I transmembrane protein belonging to the large homologous family of Toll like receptors. TLR2 acts as functional receptor for both Gram-positive and Gram-negative bacteria.
  • TLR1- cluster of differentiation 281
    Toll-like receptor 1 (TLR1) often designated as CD281 (cluster of differentiation 281), a member of the Toll-like receptor family recognizes pathogen-associated molecular pattern with specificity for gram-positive bacteria.


 
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